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In addition, the absence of widely adopted, standardized clinical assessment tools has led to inconsistencies in evaluation and referral practices

The compound incorporates N-terminal acetylation and C-terminal amidation , structural modifications commonly applied in peptide chemistry to influence molecular stability and resistance to enzymatic degradation in experimental systems

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Radioactive iodine therapy destroys overactive tissue within 3-6 months but often leads to permanent hypothyroidism requiring lifelong hormone replacement afterward