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In this case, it becomes essential to establish a system of continuous monitoring of the problem of tobacco smoking, the ultimate goal of which is to combat it, as well as to prevent the issue from motivating todays smokers to fight tobacco addiction and lead a healthier lifestyle, which is unthinkable without smoking cessation, and in the future to form a new generation of people with anti-smoking consciousness

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Peritoneal and peripheral blood mononuclear cell-derived macrophages express 7-nAChRs and vagal nerve stimulation or exogenous ACh has been shown to inhibit NF-B transcriptional activity and pro-inflammatory cytokine production [16, 31]