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49 Further evaluation on a double-blind, randomized phase 1 clinical trial in 98 patients with T2DM on current management with metformin revealed that Danuglipron was generally well tolerated and associated with minimal side effects such as nausea, dyspepsia, and vomiting comparable with the ones observed with the use of injectable GLP-1RA

Wegovy contains semaglutide as its active ingredient, the same compound found in the Type 2 diabetes medication Ozempic

Finally, we showed that pharmacological inhibition of the thioredoxin system by the chemotherapeutic drug arsenic trioxide (ATO) enhanced MTX cytotoxicity in vivo against one out of four primary human ALL cells, suggesting a novel therapeutic rationale to be further explored against ALL

Sobko, T