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They work by altering the secretion of various hormones involved in energy balance and metabolism, such as leptin, ghrelin, and insulin [10]

[30] [32] Cardiovascular risk reduction is established for specific GLP-1 receptor agonists in type 2 diabetes, and semaglutide 2.4 mg (Wegovy) has an FDA-approved indication for major adverse cardiovascular event risk reduction

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