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Most patients notice deeper sleep within the first 1 to 2 weeks, faster recovery by weeks 3 to 4, body composition changes by weeks 5 to 8, and skin and energy improvements by weeks 8 to 12

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*Correspondence: Chuan Sun, [email protected] This article was submitted to Clinical Diabetes, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

J Endocrinol Invest 41(4):383388 Azziz R, Carmina E, Chen Z, Dunaif A, Laven JSE, Legro RS et al (2016) Polycystic ovary syndrome