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While we anticipate retatrutide being a strong option for many people seeking weight loss, it may be particularly useful for anyone who falls into one or more of these categories: Didnt respond to earlier GLP-1 drugs like Wegovy, Ozempic, Rybelsus, Liraglutide, Zepbound, Mounjaro, etc Plateaued with other GLP-1s but still havent met your target weight Have a large body percentage of weight to lose (20% or more) Retatrutide is currently undergoing clinical trials necessary for it to obtain FDA approval (which is anticipated by summer) , so it's not yet available to be prescribed

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Johns Wort (an herbal antidepressant), some opioid painkillers (like tramadol, meperidine), and even the anti-parkinson medication selegiline