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The cost difference reflects business model efficiency and absence of brand-name premiums, not quality differences in the actual medication

The intake does not include a dedicated eating-disorder screen , a substance-use or alcohol screen, a validated PHQ-2 or PHQ-9 depression instrument (the suicidal-ideation question is present but bundled into the GI conditions list rather than getting its own safety context), an allergy screen, a current medications review, a diet or exercise history , a blood pressure reading , or an explicit pregnancy check

These once-weekly injectables have shown dramatic results in clinical trials, rivaling or even exceeding outcomes from some bariatric surgeries in terms of percent body weight lost