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Journal of Acquired Immune Deficiency Syndromes

3.1.1 Nuclear receptor signaling disruption 3.1.1.1 Androgen receptor antagonism Bisphenol A exhibits androgenic antagonism, functioning as a competitive antagonist that blocks androgen receptor binding and subsequently reduces ARE-mediated gene transcription, with documented effects on androgen-dependent gene expression

In clinical trials, patients using liraglutide typically lost around 58% of their body weight , compared to placebo groups (FDA approval summary for Saxenda)