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Do Not Self-Adjust Medication It can be tempting to reduce your levothyroxine dose yourself if you see a "normal" result while losing weight

The Phase 2 trial specifically tested starting at 4mg versus 2mg and found that higher starting doses produced significantly more GI side effects without faster weight loss

These lipid modifications, combined with weight loss and improved glycemic control, contribute to a more favorable cardiometabolic profile and may reduce the risk of cardiovascular events

Typically, we find that patients taking FDA-approved GLP-1 agonists such as Ozempic and Wegovy will lose 10% of weight by 6 months and 15% within 1 year