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The study illustrated improved islet yield and viability in the wild-type mice and even confirmed enhanced Nrf2 nuclear translocation, anti-oxidant expression, islet yield, and viability in rats treated with an Nrf2 activator (dh404) [131]

Note shelf life and reconstitution instructions

Antioxidants often work synergistically (eg Vitamin C regenerates Vitamin E) Not all oxidation is bad

Thus, another aspect for future research of Se at the brain barriers may be related to improving our understanding on sex-related differences, including the effects of dietary Se, selenoproteins, and selenometabolites on permeability and function of BBB, BCB as well as gut-brain axis and brain immunity