L-cells are nutrient sensitive and GLP-1 is secreted in response to glucose ( Reference Reimann, Habib and Tolhurst 21 ) , proteins ( Reference Hall, Millward and Long 22 , Reference Power, Conway and McCormack 23 ) peptides ( Reference Hira, Mochida and Miyashita 24 ) , amino acids ( Reference Oya, Kitaguchi and Pais 25 , Reference Reimann, Williams and Silva Xavier 26 ) and lipids ( Reference Lindgren, Carr and Deacon 27 )
And, even then, I wouldnt prescribe them unless they are needed for diabetes management. In August 2023, the American Academy of Pediatrics endorsed GLP-1s as part of an obesity treatment plan for youths 12 and older
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: The selenium and vitamin E cancer prevention trial (SELECT)
doi: 10.1046/j.1440-1681.1999.03157.x