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Oxidative stress may contribute to processes involved in cardiovascular disease, including endothelial dysfunction, LDL oxidation, inflammation, mitochondrial injury, and plaque formation

New insight into glucose metabolism dysregulation in TBI Current consensus suggests that primary TBI immediately resulting from mechanical stress and displacement of brain tissues is compounded by progressive secondary injury (damage to the BBB, protein aggregation, etc.) that is partially mediated by metabolic dysfunction [27]

Pairwise structural alignments were determined using TM-align (see Methods) for full 3D structures (global alignments) or tunnel-interacting residues within structures (local alignments)

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