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Liver, yeast, and egg yolk contain also very high amounts of folate 1,33,50,60,75,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105

This process triggers a potent inflammatory response, characterized by the upregulation of pro-inflammatory cytokinesincluding IL-1 and interferon- (IFN-)and the concomitant downregulation of tight junction proteins, thereby compromising mucosal barrier integrity 76

A possible persulfidation is also reported but the targeted cysteine(s) not identified (Jurado-Flores et al., 2021)

A 6-h treatment with thioacetamide led to a significant increase in ROS levels compared with the control group, but pre-treatment with 2APB effectively mitigated this oxidative stress in the liver of both wild-type and hepsin / mice