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For instance, hormone replacement therapy (HRT) or pharmacological agents mimicking estrogen may enhance the protective role of MBOAT1, thereby inhibiting ferroptosis and lipid peroxidation (Liang et al., 2023)

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On another note, someone with severe adrenal insufficiency can experience some of the more severe side effects

Moreover, this pathway promotes the polarization of macrophages towards an M1-type pro-inflammatory phenotype, thereby playing a crucial role in anti-infective immunity and inflammatory responses