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In addition to its role in mitochondrial activity, acetyl L-carnitine (ALC) is involved in the production of the key brain neurotransmitteracetylcholine and is also able to donate its acetyl group in a number of other biochemical reactions

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The sequential approach The ATTAIN-MAINTAIN trial introduces a compelling treatment strategy: using tirzepatide and orforglipron sequentially rather than choosing one or the other