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These effects are measurable but significantly smaller than what GLP-1 medications achieve
Further, there was variability among animals and the study population was relatively small (especially in cats), and this might have obscured the identification of relationships between the degree of obesity and outcomes of weight reduction
Oral semaglutide is available at $289/mo (or $249/mo on the 6-month plan) if you prefer a different delivery method, and all medications are HSA/FSA eligible with no insurance required
Further support for the combination of an SGLT2 inhibitor with agents that reduce appetite (and/or increase satiety) is provided by a clinical trial of canagliflozin and phentermine, given either in combination or each drug alone
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