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Glucagon- and GCGR-positive cells were manually counted in five mouse islets using Fiji (version 1.53t, National Institutes of Health, MD, USA, No immunoreactivity in pancreatic islets was observed with the ab75240 antibody in Gcgr / mice [20]

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Non-clinical and first-in-human characterization of ECC5004/AZD5004, a novel once-daily, oral small-molecule GLP-1 receptor agonist

Stepped-care beats one-size-fits-all approaches : Personalizing treatment based on early response patterns rather than fixed timelines reduces costs by 42% while achieving comparable or superior outcomes to standard behavioral interventions