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HRT is the injection of synthetic hormones into the body to increase those levels in the body and ensure your body is functioning normally, but peptides can encourage your body to produce those hormones on its own, decreasing the need for synthetic hormones altogether

It has been used extensively in animal studies, human cell models, and increasingly in off-label therapeutic settings, with minimal toxicity or organ stress reported

These effects were mediated through downstream activation of transcription factors including c-Fos, c-Jun, and EGR-1, which regulate genes involved in cell cycle progression, extracellular matrix remodelling, and angiogenic signalling

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