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Timing: Start immediately post-surgery or injury (within 24-48 hours optimal)

Research indicates that reduced glutathione supplementation supports cognitive performance through multiple pathways beyond simple antioxidant protection

During the UKPDS, there was a 16% reduction in CVD events (combined fatal or nonfatal MI and sudden death) in the intensive glycemic control arm that did not reach statistical significance ( P = 0.052), and there was no suggestion of benefit on other CVD outcomes (e.g., stroke)

These activators have shown neuroprotective efficacy in animal models of chemotherapy-induced peripheral neuropathy (CIPN)