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Preliminary results of a phase II study of retifanlimab (PD-1 inhibitor) plus or minus epacadostat (IDO1 inhibitor) in combination with bevacizumab and hypofractionated radiotherapy for recurrent glioblastoma: NCT03532295

Mouse perfusion studies were supported by an unrestricted grant to JJH from the Novo Nordisk Center for Basic Metabolic Research (Novo Nordisk Foundation, Denmark, NNF10CC1016515) and by a grant to JJH from the European Research Council (grant 695069)

In the periphery of the control grafts, we also observed hyperintense signals from small separate lobulated fat massesstructures that may eventually develop into cysts or foci of calcification and are a common clinical complication of fat grafting

As this process continues, depending on the severity of inflammation, a more concerted effort is needed, over a period of time, from both the innate and acquired immune systems