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In children, there is still a lack of research on the safety and effectiveness of medications in pediatric populations

Support around access to food is a particular issue due to impaired satiety and, because of this, people with PWS eat excessive amounts of food (hyperphagia)

Much of this evidence has recently been reviewed in detail elsewhere [2,3].A recent exhaustive review of the literature complete with citation tracking demonstrated that, within the medical profession, APAP is widely considered safe when used as directed in the pediatric population [5]

198 Effective immunization of this population is necessary to reduce the infection and death caused by SARS-CoV-2