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Gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation are the most commonly reported, typically most pronounced during dose titration

Another study showed 2% alpha-arbutin paired with 10% Trihydroxybenzoic Acid Glucoside and sunscreen faded dark spots and melasma without causing irritation

Impact on Hormonal Balance Stress doesn't just affect your metabolismit directly influences the reproductive hormones already disrupted in PCOS: Elevated stress hormones can increase androgen production , potentially exacerbating symptoms like hirsutism, acne, and hair loss