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It may accomplish this function through the process known as angiogenesis

24 h) attenuates the HG-induced decrease in Wnt / -catenin signaling proteins in HMCs

This mechanistic distinction means the compound could theoretically be combined with appetite-suppressing peptides for a protocol that simultaneously reduces energy intake (GLP-1) and restores adipocyte energy expenditure (NNMT inhibition) though this remains purely theoretical without published combination data