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Normal serum levels in healthy human subjects are 150-250 microgram/L for IGF-1 and 400-900 microgram/L for IGF-2
Also, some research suggests that Rosmarinus officinalis leaf extracts and some of their metabolites like indirubin (IND), prototype ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 6-formylindolo[3,2-b] carbazole (FICZ) and pityriazepin (PZ) inhibits the AhR activation (Aryl hydrocarbon receptor) in human keratinocytes