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(1972) TA 98 20 or 40 mmol plate S9 male mice - Braun et al

New delivery mechanisms, such as microneedle patches, sustained release implants, and targeted liposomal carriers, are being developed to enhance tissue targeting and minimize dosing frequency

Sometimes, the effect of the procedure can last up to several months

Phase (approx.) Cagrilintide dose Frequency Weeks 14 0.25 mg Once weekly Weeks 58 0.5 mg Once weekly Weeks 912 1.0 mg Once weekly Weeks 1316 1.7 mg Once weekly Week 17 onward 2.4 mg (max studied) Once weekly This step-wise schedule mirrors the titration used in cagrilintide and CagriSema studies ( Lau et al., Lancet 2021