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9 compounds showed correlation with all three disease activity scores: dihydroxy-acetone-phosphate (DHAP), oxaloacetate (OAA), glucose 1-phosphate (G1P), hexose-phosphate, deoxyribose-phosphate, uracil, acetoacetate, geranyl pyrophosphate (GPP), and indole-3-carboxylic acid
The delta sleep-inducing peptide inhibits CRH at the hypothalamic level, reducing the signal that drives ACTH release and, downstream, cortisol secretion from the adrenal glands
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Growth and mortality were comparable with controls
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