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Although direct comparisons between formulations are not feasible, these data support the hypothesis that semaglutide dose intensification may confer additional metabolic benefits across delivery routes in Japanese patients with T2DM

BMC Musculoskelet Disord 23:465 Li J, Fu LZ, Liu L, Xie F, Dai RC (2017) Glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide alters bone marrow exosome-mediated miRNA signal pathways in ovariectomized rats with type 2 diabetes

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Early changes may be subtle and are often accompanied by side effects as the body adjusts to the medication