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The authors concluded: Further research is needed to determine if there is a true cause and effect relationship in the association identified in this investigation and to understand the trade-offs between the benefits and risks of GLP-1 RAs. Also in June, the European Medicines Agency safety committee warned that semaglutide (active substance in Ozempic, Rybelsus and Wegovy) may cause the NAION optic neuropathy described earlier in this article

U.TakatsukaT.MiyamotoS.SasakiM.et al

The side effects are similar to semaglutide GLP-1, primarily gastrointestinal discomfort

Individually, each therapy offers substantial benefits