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The findings on antidepressants by Yildiz et al [7] are in line with a prior systematic review and meta-analysis from 2016 focusing on randomised, double-blind, placebo-controlled trials of second-generation antidepressants adjunctive to a mood stabiliser or an antipsychotic in patients with acute bipolar depression [14]

Tumor growth is driven by intricate interactions between the tumor microenvironment (TME) and immune cells, inflammatory mediators, extracellular matrix remodeling, hypoxia, cancer stemness, cellular senescence, and metabolic dysregulation