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Because there is no combination-level trial, this timeline is a synthesis of the individual-peptide literature and the protocols own structure treat it as a framework for observation, not a guarantee

We further noted that the use of this methodology would, in general, reduce the beneficiary coinsurance rate and copayment amount for APCs for which the payment rate changes as the result of the reconfiguration of APCs and/or recalibration of relative payment weights (68 FR 63459)

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