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Patients should be advised on strategies to manage these symptoms and encouraged to report any persistent or severe gastrointestinal issues to their healthcare provider

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To investigate whether DAM and DAA are associated with neurodegeneration in GCLC-KO mice, we conducted qRT-PCR analyses of DAM and DAA-related genes using cortical samples from 4-month-old GCLC-KO and WT mice (Fig

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If disease activity remains inadequately controlled, treatment should escalate to combination conventional synthetic DMARDs or biological agents following a treat-to-target approach

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