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Evidence for functional nicotinic receptors on pancreatic beta cells

It has been shown that GLP-1RA semaglutide can improve working and spatial memory in transgenic AD modelling APP/PS1/tau (3xTg) mice, promote the release of anti-inflammatory factors and inhibit the production of pro-inflammatory factors in the cerebral cortex and hippocampus, as well as reduce the deposition of -amyloid in the CA1 subfield of the hippocampus

Signaling pathway components (EGR1/NEDD9/FAK/AKT): early growth response 1, neural precursor cell expressed developmentally downregulated 9, focal adhesion kinase, protein kinase B

However, this may vary depending on the nature of the fused biologic