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Up to now, they were not investigated in parallel, in duodenal ulcers (16, 17), which should be important considering the dual significance of the NO-system (8), and the NO-systems particular role in skin and gastrointestinal lesions healing (5, 18, 19) as well as fistulas healing (10, 12)

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showed that in the emergency department, the circulating concentration of syndecan-1, a marker of glycocalyx degradation, correlates with the fluid requirement, severity of sepsis, extent of organ dysfunction, and risk of mortality, but a direct relationship with glycocalyx degradation has not been identified (123)

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