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Environmental factors such as pollution, UV exposure, stress, and lifestyle habits can increase oxidative stress levels, which is why antioxidants are an important area of interest in skin health
The process of freezing and thawing can create ice crystals that damage the peptides structure, causing aggregation and reducing its bioactivity
Part of the response to infection is activation of macrophages to produce a mixture of oxygen and other radicals that are cytotoxic to engulphed micro-organisms
While no research yet shows a connection to Hashimotos, I wanted to make note that in some cases, individuals may have normal blood levels of folate, but the folate may not be getting to the brain due to autoimmune folate receptor antibodies (FRAs), which block the transport of folate into the cerebral spinal fluid (CSF)
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