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Potential for abnormal tissue growth or scar tissue formation
Since E2f1 plays a key role in both post-natal proliferation of cells (18) and early pancreas development by targeting Pdx1 and Ngn3 expression through the Cdk4 pathway (19), the deletion of the E2f1 gene using Rip-Cre mice may affect early -cell differentiation and mass
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Outer Membrane Vesicles and Soluble Factors Released by Probiotic Escherichia coli Nissle 1917 and Commensal ECOR63 Enhance Barrier Function by Regulating Expression of Tight Junction Proteins in Intestinal Epithelial Cells
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