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NMO is mainly caused by auto-anti-AQP4 antibodies 282 that initially attack astrocytic endfeet, 283 leading to complement-mediated lysis and destruction of the glial limitans and astrocyte degeneration, which in turn cause the other pathophysiological sequalae (Fig

The low glutamate diet improves cognitive functioning in veterans with Gulf War Illness and resting-state EEG potentially predicts response

Before starting either agent, comprehensive provider evaluationnot marketing claims or social media protocolsshould establish appropriateness and monitor for adverse effects

Most of this information came from the Cleveland Public Library which houses Little's chess scrapbooks and manuscripts