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Its use as a weight-loss drug has gripped the cultural zeitgeist faster than fad diets

196 The use of spironolactone and oral contraceptives has been shown to be more effective than either alone for PCOS-related unwanted hair growth, and is often recommended for treating moderate-to-severe unwanted hair growth, or mild unwanted hair growth that is not sufficiently resolved after six months of treatment with oral contraceptives

To avoid long-term effects, make sure you prioritize close communication with a healthcare provider, gradual dose increases, and routine monitoring to catch issues early

In SURMOUNT-1, the 15 mg group lost an average of 20.9% body weight over 72 weeks