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Higher risk groups include: People starting GLP-1 medicines for the first time People whose dose is increased too quickly People who eat large, oily, or very sweet meals People with type 2 diabetes using insulin or sulfonylureas People with previous pancreatitis People with gallstones or gallbladder disease People with severe digestive disorders People with gastroparesis People with kidney disease People with dehydration risk People with diabetic retinopathy People with a personal or family history of medullary thyroid carcinoma People with Multiple Endocrine Neoplasia syndrome type 2 People with active mood disorders or suicidal thoughts People planning surgery or procedures under anaesthesia Patients With Diabetes Vs Non-Diabetic Users People with diabetes may use GLP-1 medicines to improve blood sugar control and support weight management

In addition to the effects on weight loss and diabetes control both cardiovascular risk factors other mechanisms of action have been proposed for the entire class of GLP-1 agonists, Jayne Morgan, MD, a cardiologist and the executive director of Health and Community Education at the Piedmont Healthcare Corporation in Atlanta, GA, not involved in the study, told MNT