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Description

Inflammation-associated oral mucosal melanin hyperpigmentation Under circumstances that are not well defined, certain inflammatory cytokines and mediators have the capacity to promote the production of -MSH by oral melanocytes and keratinocytes and to upregulate the expression of MC1R of melanocytes resulting in increased biosynthesis of melanin

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To exclude the loss of components during the fractionation procedure, the solute and eluate of CAF-CM were re-pooled together and tested

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