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Seek urgent same-day assessment or call 999 for emergency care if experiencing: Severe chest pain Severe shortness of breath Fainting or collapse Acute or rapidly worsening neurological deficits (such as new limb weakness, sudden gait disturbance, or bladder/bowel dysfunction) Persistent or worsening anaemia symptoms despite treatmentincluding breathlessness, chest discomfort, palpitations, or extreme fatigueshould trigger medical review

10.1111/jcmm.16458 73 LiQ.HanX.LanX.GaoY.WanJ.DurhamF.et al (2017)

Instead, it concentrates in the gut, where it activates a lysosomal stress response

After the appropriate incubation time, the cells were washed once with DPBS Ca 2+ /Mg 2+ (Invitrogen)