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It is not a sea of perfect five-star outcomes, and it is not a collection of complaints

Regulation of WNT5A and WNT11 during MSC in vitro chondrogenesis: WNT inhibition lowers BMP and hedgehog activity, and reduces hypertrophy

Dysbiosis during this transition underlies elevated ketosis risk: the decline of VFA-producing taxaincluding Ruminococcus , Prevotella , Selenomonas , and Succinivibrionaceaeimpairs propionate fermentation pathways and reduces gluconeogenic precursor supply, while the concurrent expansion of opportunistic taxa such as Mycoplasma and Saccharimonas further destabilizes ruminal homeostasis (Table 2), collectively contributing to hypoglycemia, excessive mobilization of body fat, and ketone accumulation, which compromise lactation, reproductive performance, and offspring health 47,55,56,57

These fibroblasts are central to maintaining the structural framework of the skin, as they secrete collagen and related matrix proteins that provide tensile strength and resilience