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They work through a combination of many events, including weight loss and improving insulin sensitivity, says Cheng-Han Chen, MD, an interventional cardiologist and the medical director of the structural heart program at MemorialCare Saddleback Medical Center in Laguna Hills, California

If you think you may have a medical emergency, call 911 (or your local emergency service) immediately.

In the SELECT trial, semaglutide reduced the incidence of major adverse cardiovascular events, including heart attack and stroke, by 20% in individuals with established cardiovascular disease and obesity but without diabetes [10]

Every assessment begins with your Glomerular Filtration Rate (GFR), the primary metric used by our Specialist prescribers to determine if medications like Mounjaro or Wegovy are safe for your specific stage of kidney disease