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This has prompted the exploration of novel molecular strategies, including the use of peptides as therapeutic agents [49-53]

The most recognizable sequence of classic BPC-157 is: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val It is this framework that is the reference point for most studies on fibroblast migration, nitric oxide-related signals, endothelial integrity, angiogenesis, and repair processes in exposed tissues

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Furthermore, functional genomics approaches, including gene knockout and overexpression studies in animal models, have helped clarify the physiological roles of specific ORs (25)