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scramble: 32.5% 1.8%, n = 7

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By using multiple fluorescence immunohistochemistry techniques, multi-channel information about cell composition and spatial arrangement can be obtained, enabling high-dimensional analysis of the tumor microenvironment and providing precise diagnosis and subsequent targeted therapy assistance for tumors

DNA and RNA synthesis is inhibited by the dual inhibitory action of MTX-PGs on thymine synthase and DHFR, which results in the inhibition of purine and pyrimidine de novo synthesis (Giletti and Esperon 2018