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Metal-coordinated NIR-II nanoadjuvants with nanobody conjugation for potentiating immunotherapy by tumor metabolism reprogramming

NO-agents showed NO-system involvement (L-arginine (therapy effect, continuously affecting tongue, and intermittently affecting stomach, thereby a slight effect) and L-NAME (tongue lesions aggravation) and together, the responses antagonized each others effects)

Exenatide improves excessive daytime sleepiness and wakefulness in obese patients with type 2 diabetes without obstructive sleep apnoea