does tirzepatide make you lose muscle mass GLP-1 and Loss: Semaglutide, & Lean How Semaglutide and Tirzepatide Affect

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These medications work through multiple complementary mechanisms: Appetite Regulation: Activate receptors in brains appetite centers Reduce hunger signals Increase feelings of fullness Decrease food cravings Gastric Effects: Slow stomach emptying Prolong satiety after meals Reduce portion sizes naturally Metabolic Benefits: Improve insulin sensitivity Better blood sugar control Reduce inflammation Positive cardiovascular effects The combination of these effects produces weight loss 2-4x greater than older medications

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Pregnancy: Rising cortisol and oestrogen levels, combined with rapid abdominal expansion, make striae gravidarum extremely common, with prevalence reported above 70% in many studies