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Ozempics website notes that it "acts as a GLP-1 receptor agonist that selectively binds to and activates the GLP-1 receptor, the target for native GLP-1." The medication also lowers fasting blood glucose by stimulating insulin secretion, according to Ozempics website

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Over the past couple of yearsspanning two administrationscoverage of GLP-1s for weight loss has been controversial: November 2024: the Biden administration proposed a major shift, allowing CMS to cover GLP-1s like Wegovy and Zepbound for weight loss