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239 Elevated expression of ATG genes, including ATG4B, ATG4D, ATG5, and BECN1, underscores its mechanistic relevance, 240 and ATG4B knockdown sensitizes cells to therapy

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9 Challenges and future directions 9.1 Challenges in integrating antioxidants and nanotechnology in cancer therapy Ensuring Safety and Efficacy : Nanoparticles pose several challenges in ensuring safety and efficacy in antioxidant therapies