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Secondly, these molecules induce substantial weight loss because of their dose-dependent central inhibition of energy intake and mitigation of food cravings [4]

Addiction/mental health A study of more than 2 million people with diabetes taking the popular weight-loss drugs found the medications were associated with reduced risks of seizures and addiction to substances such as alcohol, cannabis, stimulants and opioids

The finding of decreased brain levels of TPP in the presence of normal levels of free thiamin and TMP suggests altered TPP synthesis rather than poor thiamin bioavailability

The following parameters were evaluated: Sholl index (number of dendrite intersections per radius)