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Conclusion: Our results demonstrate the advanced potential of our 3D liver tissues as a reliable preclinical screening tool for NASH drug discovery

doi: 10.1002/hep.30251 34

* Correspondence: Xi Wu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In brief, the peak area of the metabolite was normalized to the peak area of an isotopically labelled internal standard with similar elution time, both in samples from culture medium and external standard library dilutions